Safety, efficacy, and tissues residues of ivermectin in reindeer
AbstractSafety, efficacy, and tissue residues of ivermectin, a broad spectrum parasiticide, were determined in Alaskan reindeer (Rangifer tarandus). Reindeer treated at 5 times and 10 times the standard dose of 200 mcg/kg had no detectable physical or behavioral reactions to ivermectin injected subcutaneously in the mid-cervical area. Ivermectin eliminated essentially 100% of reindeer warble larvae (Hypoderma (Oedemagena) tarandi). Tissue levels of ivermectin in back fat, injection site, muscle, liver, and kidney collected 3, 10, 17, and 24 days post injection were determined. All tissues levels rapidly declined and were approaching low unmea-surable amounts at the end of the 24 day test period. Ivermectin is a safe effective parasiticide that has been used successfully to threat thousands of reindeer in Alaska.
Authors retain copyright and grant Rangifer irrevocable and non-exclusive right of publication with the work simultaneously licensed under a Creative Commons Attribution License (CC-BY). This means, among other things, that anyone is free to copy and distribute the content, as long as they give proper credit to the author(s) and the journal. For further information, see Creative Commons website for human readable or lawyer readable versions.